Edwin Grech (27 September 1928 – 15 March 2023) was a Maltese doctor and politician from the Labour Party. Grech was elected to the Parliament of Malta from District 2 in 1992 and 1996. He was Minister of Social Security from 1996 to 1998. He died in 2023. His funeral was attended by Prime Minister Robert Abela, other ministers and former prime minister Joseph Muscat. His daughter Karin Grech was murdered in 1977 by a letter bomb. His nephew Bernard Grech was leader of the Nationalist Party from 2020 until his resignation in 2025.