Sir Ugo Pasquale Mifsud (12 September 1889 - 11 February 1942) was a Maltese politician, the 3rd Prime Minister of Malta under British home rule, and the first to serve a full term in power. He held office from 1924 to 1927 and from 1932 to 1933. He was a member of the Nationalist Party and the Maltese Italian community.