1592, May 7

Plague Epidemic

A plague epidemic begins, killing around 3,000 people until its end in September 1593. 

Plague Epidemic

1566, March 28

Valletta Founded

The founding of Malta's new capital city, Valletta. A general strengthening of Malta's fortifications is undertaken. 

Valletta Founded

1565, September 13

Turkish Forces Retreat

Turkish forces retreat from Malta. 

Turkish Forces Retreat

1565, September 7

Grande Soccorso

Don Garcia's reinforcements, known as the Grande Soccorso ('great relief'), finally arrive. 

Grande Soccorso

1565, July 12

Senglea Besieged

Senglea is besieged. 

Senglea Besieged

1565, July 9

Reinforcements return to Sicily

Reinforcements sent by Viceroy Don García de Toledo fail to make harbour, as a result of the fall of Fort St. Elmo, and return to Sicily. 

Reinforcements return to Sicily

1565, July 8

Turkish forces reinforced

The Turkish forces are reinforced with the arrival of 29 vessels and 2,500 warriors accompanied by the Bey of Algiers. 

Turkish forces reinforced

1565, July 3

Turkish fleet transported

The Turkish fleet is transported on rollers, overland, from Marsamxett Harbour to Grand Harbour, in preparation for an assault on Senglea. (to 12 July) 

Turkish fleet transported

1565, June 29

Four galleys land

Four galleys land in the north of Malta, bringing 600 soldiers, 42 knights, 56 gunners and numerous volunteers, to reinforce the Island's defences; they walk to Mdina by night, and then on to Birgu the following morning. 

Four galleys land

1565, June 23

Knights beheaded

Turkish commanders order all the dead Knights found in St. Elmo to be beheaded; their mutilated bodies are floated across Grand Harbour on planks towards the bastions of Senglea and Birgu. 

Knights beheaded

1565, June 23

Fort St. Elmo falls

Fort St. Elmo falls to the Turks. 

Fort St. Elmo falls

1565, May 20

Turkish fleet anchors

The Turkish fleet anchors at Marsaxlokk, moved to Żejtun and sets up camp at Marsa. 

Turkish fleet anchors

1565, May 19

Turkish vessels sheltered

A storm prevents the Turkish fleet from landing at Marsaxlokk; the vessels are sheltered in Ġnejna Bay and at Għajn Tuffieħa. 

Turkish vessels sheltered

1565, May 18

Ottoman armada sighted

Ottoman armada sighted off the coast of Malta, signalling the start of the Great Siege of Malta. 

Ottoman armada sighted

1565, April 16

Evacuation to Sicily

Evacuation to Sicily of 'a great number of people' from Malta, including large numbers of Maltese nobility, in anticipation of the imminent invasion. (to 13 May) 

Evacuation to Sicily

1565, March 30

Don García de Toledo y Osorio

The Spanish Viceroy of Sicily, Don García de Toledo y Osorio, tours the Island's fortifications; he promises the Knights that in the coming invasion they need only hold out until June, when he would bring his armada back to assist Malta. 

Don García de Toledo y Osorio

1565, March 30

Ottomans leave Constantinople

Ottoman fleet leaves Constantinople for Malta; Queen Elizabeth remarks: 'If the Turks should prevail against the Isle of Malta, it is uncertain what further peril might follow to the rest of Christendom.' 

Ottomans leave Constantinople

1564, December

Ottoman war council

The Ottoman war council in Constantinople decrees that Malta is to be invaded and conquered. 

Ottoman war council

1561

Holy Inquisition

The Holy Inquisition is established in Malta. Domenico Cubelles is the first Inquisitor. 

Holy Inquisition

1560

Corsairing activities

The Knights of Malta escalate their corsairing activities in the western Mediterranean. (to 1565) 

Corsairing activities
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